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Generally, a person can only get HSV-2 infection during sexual contact with someone who has a genital HSV-2 infection.Transmission can occur from an infected partner who does not have a visible sore and may not know that he or she is infected.At least 50 percent of sexually active men and women acquire genital HPV infection at some point in their lives.

HSV-1 can cause genital herpes, but it more commonly causes infections of the mouth and lips, so-called ? HSV-1 infection of the genitals can be caused by oral-genital or genital-genital contact with a person who has HSV-1 infection.

Genital HSV-1 outbreaks recur less regularly than genital HSV-2 outbreaks. There is no treatment that can cure herpes, but antiviral medications can shorten and prevent outbreaks during the period of time the person takes the medication.

Genital HSV-2 infection is more common in women (approximately one out of four women) than in men (almost one out of five).

This may be due to male-to-female transmissions being more likely than female-to-male transmission. HSV-1 and HSV-2 can be found in and released from the sores that the viruses cause, but they also are released between outbreaks from skin that does not appear to be broken or to have a sore.

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